enrichMiR: miRNA target enrichment analysis
This app will allow you to identify miRNAs whose targets are enriched among genesets of interest or a differential expression signature, and produce related visualizations. Although the app was chiefly developed (and benchmarked) for miRNAs, some support is also offered to run the same analyses using RNA-binding proteins.
The app has two main functionalities:
- performing target enrichment analysis , either comparing your gene set of interest to a background set, or using the results of a differential expression analysis (DEA).
- generating foldchange cumulative distribution (CD) plots comparing targets and non-targets (requires the results of a differential expression analysis as input).
To get started, take a quick tour of the app, or browse the help on the upper-right corner.
Please report any bug in the github repository .
enrichMiR version 0.99.32 ; Schratt lab
Select Species and Collection
Note that some collections (e.g. scanMiR) might take a moment to load.
Specify expressed miRNAs (optional)
miRNA expression can be used to restrict and annotate the enrichment analysis. This information can either be given manually, provided by uploading a miRNA profile, or fetched from pre-loaded miRNA expression profiles
Choose between the two following input options
You may either upload the results of a differential expression analysis (DEA), or provide a set of genes of interest against a background set.