You may upload your own SummarizedExperiment (SE) object saved as a R .rds file. Once uploaded, it will be added to the list of available objects (in the dropdown list on the top left). For instructions on how to optimally prepare the object, click here .

If your the row names of the object are dot-separated IDs, such as 'ensemblID.symbol' (you can view this in the 'Features' tab), you may also enter just the genes symbols and the corresponding rows will be fetched.

Important: Note that the number of input genes is capped to

This app allows you to browse and plot the multi-omics data from our study on the impact of symmetrical copy-number variations (CNV) of the 7q11.23 region on human iPSC-derived neurons.

7q11.23 CNVs lead to a pair of multisystemic syndromes with shared and opposite features: while the hemideletion of the region causes Williams-Beuren syndrome (WBS), its hemiduplication leads to 7q microduplication syndrome (DUP/7Dup). We profiled the transcriptome, translatome and proteome of induced neurons from both patient-derived and isogenic iPSC (see paper for more detail), and this data is made available for browsing and visualization through this portal.